Biostimulators: The Next Generation of Collagen-Stimulating Treatments at Karee Hays Esthetics
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If you’ve noticed your skin feeling thinner, less firm, or less radiant over time, you’re not imagining it. Collagen, the protein that keeps our skin firm and youthful—naturally declines every year after our mid-20s. The good news? At Karee Hays Esthetics, we specialize in biostimulators—advanced treatments that activate your body’s own collagen production for long-term skin rejuvenation.
Unlike fillers that simply add volume, biostimulators work beneath the surface to rebuild your skin’s foundation, restoring elasticity, tone, and overall glow. Two of our most loved collagen treatments are Hyperdilute Radiesse (injectable) and PRX (topical), both delivering natural, lifted, and radiant skin with minimal downtime.
What Are Biostimulators?
Biostimulators are injectable or topical treatments designed to stimulate the skin’s natural collagen and elastin production. Instead of instantly filling lines, they improve the skin’s quality and firmness over time. Results are gradual, subtle, and long-lasting—perfect for anyone who wants to age gracefully without looking “done.”
At Karee Hays, we have several collagen-stimulating options tailored to your goals:
Radiesse: Injectable Collagen Remodeling
Best For: Crepey skin, laxity, dull tone, and loss of structure
How it works:
Hyperdilute Radiesse uses a thin, strategically diluted form of the well-known dermal filler Radiesse (calcium hydroxyapatite). When injected just under the skin, it acts as a collagen stimulator rather than a volumizer. The formula signals the body to produce new collagen and elastin, improving texture and firmness from within.
Treatment areas:
Midface
Temples
Lower face and jawline
Temples
Chin
Arms, knees, and body areas showing thinning or crepiness
Results:
Most patients notice smoother, firmer skin within a few weeks, with collagen production continuing to improve for months.
Why patients love it:
Minimally invasive
Gradual, natural results
Improves skin quality, not just volume
This Month’s Special:
Buy 2 syringes of Radiesse and get 1 free!
If you’ve been curious about skin tightening or want to refresh your neck and jawline before the holidays, now’s the perfect time to try this collagen-stimulating injectable.
PRX: The “No-Peel” Collagen Biostimulator
Best For: Dull, aging skin; uneven tone; fine lines
How it works:
PRX, is a unique TCA (trichloroacetic acid) formula that stimulates collagen without peeling or downtime. Unlike traditional chemical peels, PRX penetrates the dermis to activate fibroblasts—the cells responsible for collagen production—while leaving the top layer of skin intact. The day of this treatment you will leave GLOWING and it only gets better!
Treatment areas:
Face, neck, chest
Hands and body
Safe for all skin tones and seasons
Results:
Skin looks instantly refreshed and brighter, with cumulative collagen improvement over a series of sessions. PRX can be performed alone or combined with other treatments like microneedling! We find the best results are with 4 weekly treatments.
Why patients love it:
Zero downtime
Immediate glow
Long-term collagen remodeling
✨ Coming in December: Special PRX package pricing! Stay tuned for details on our limited-time PRX offer—just in time for glowing, holiday-ready skin.
Why We Love Biostimulators at KH
At Karee Hays Esthetics, we take a personalized approach to collagen restoration. Whether you need full-face rejuvenation or targeted tightening, biostimulators like Hyperdilute Radiesse and PRX help create healthier, stronger, more radiant skin that lasts.
These treatments pair beautifully with injectables, laser resurfacing, and medical-grade skincare for a complete anti-aging plan.
Ready to See the KH Difference?
If you’re ready to strengthen, smooth, and rejuvenate your skin from within, book a consultation at Karee Hays Esthetics in Nashville. Our team will customize a plan using biostimulators and other advanced treatments to help you achieve that signature KH glow—naturally.