Biostimulators

Advanced injectable treatments designed to stimulate collagen and enhance natural skin quality over time

  • Encourages long-term collagen production for firmer, healthier looking skin
  • Improves skin quality gradually while preserving natural facial balance
  • Performed with precision using a skin health focused, regenerative approach
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What Are Biostimulators and How Do They Support Skin Quality?

Biostimulators are injectable treatments designed to activate the skin’s natural collagen and regenerative processes to improve overall skin quality over time. Rather than creating immediate volume, these treatments work gradually to strengthen the skin’s structure, enhance firmness, and refine texture. Common biostimulators such as Sculptra injections, Radiesse filler, and PRF based treatments encourage the body to rebuild collagen for longer lasting results. As collagen production increases, skin appears smoother, more even, and more resilient. This approach supports natural looking rejuvenation while preserving facial balance and expression.

Why Choose Biostimulators?

Natural collagen stimulation without surgery

Biostimulators improve skin quality by encouraging the body’s own collagen production, delivering noticeable improvement without surgical intervention.

Gradual, long lasting results

Unlike traditional injectables that focus on immediate change, biostimulators work over time to strengthen skin structure and firmness for results that evolve naturally.

Versatile treatment options

Biostimulators can be used across multiple areas of the face to improve texture, tone, and resilience while maintaining facial balance.

Refined, natural looking rejuvenation

By enhancing skin from within, biostimulators support smoother, healthier looking skin without altering natural facial movement or expression.

Hear From Patients Like You

I visited Karee Hays Esthetics for botox injections & it was such a great experience! I was first impressed by how sweet & attentive the entire staff was when I arrived. I felt very welcomed by everyone I met. Sophie did my injections & she was so personable that I felt like I had known her for years. She was very thorough in making sure she was using the best product for the results I was looking for & what would work best for my skin. Karee is also one of the sweetest people ever! She was so excited to see the results when I came back for my follow up. I will definitely be back for more skin care treatments here. Absolutely wonderful experience!

-A. O.

Sophie did such a good job. She’s amazing with a needle and makes you feel so calm. You can tell that she knows what she’s doing. She’s also the coolest girl ever!!!! She also gave my fiancé PRP injections, and he loves it!

- A. B.

I cannot say enough good things about Karee Hays Esthetics! From the second you walk in, you are treated with such kindness! The products, services, and most importantly to me, the people are the absolute best. The knowledge and expertise are unmatched. I recommend them to everyone!

- A. J.

KH is the best place! They are so great and offer excellent service! Sophie and Ashley are the absolute best!

- L. G.
Karee Office

Meet Karee Hays

Karee Hays is a medical esthetician and skincare specialist with advanced training alongside leading dermatologists and plastic surgeons. Since opening Karee Hays Esthetics in Nashville in 2012, she has focused on non-surgical aesthetic treatments that enhance natural beauty through education, ingredient science, and precision care. Her approach emphasizes facial balance, skin quality, and results that appear refreshed and well proportioned.

Biostimulators FAQs

Biostimulators are injectable treatments designed to stimulate the body’s natural collagen production, improving skin firmness, texture, and quality over time.

Treatments include Sculptra injections, Radiesse filler, PRF injections, and PRFM injections, selected based on skin needs and treatment goals.

Sculptra injections use poly L lactic acid to gradually stimulate collagen production, helping restore structure and firmness. Many patients ask how long does Sculptra last, and results can often last up to two years with proper treatment planning.

Radiesse filler provides immediate structural support while also stimulating collagen, whereas Sculptra works gradually over time. The choice between Radiesse vs Sculptra depends on skin condition and desired outcome.

Radiesse is a biostimulatory filler made with calcium hydroxylapatite. Radiesse treatment supports collagen production while improving firmness and contour.

PRF treatment uses platelet rich fibrin derived from the patient’s own blood to support tissue regeneration and collagen stimulation.

PRFM treatment is an advanced form of platelet rich fibrin that provides longer lasting growth factor release, commonly used for skin rejuvenation and PRFM under eye treatment.

PRF injections and PRFM injections use the patient’s own biological material and are considered safe when performed by a trained provider.

Yes. PRF under eyes and PRFM under eye treatments are commonly used to improve skin quality, texture, and brightness in the delicate under eye area.

Yes. Biostimulators can be combined with other injectable treatments or skin focused services to support comprehensive facial rejuvenation.

*Through a presumed mechanism of action of collagen remodeling

Skin Rejuvenation Has Never Been Easier


Location:

2309 Crestmoor Road, Suite 200
Nashville, Tennessee 37215

Hours:

Monday-Thursday: 9:00am-6:00pm
Friday: 9:00am-4:00pm